摘要 |
The present disclosure is directed to a fluid pumping mechanism that uses differential pressure to drive flow through one or more culture chambers. Fluid contained within a first chamber can be caused to flow through one or more culture chambers and thence to a second chamber upon establishment of a pressure differential between the two chambers. The differential pressure system can induce either steady state or pulsatile flow through a culture chamber. In one embodiment, a culture chamber can be held at a high or low pressure hydrostatic state through utilization of the disclosed systems.
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