The instant invention provides for compounds which comprise substituted thioquinazolinones that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.
申请公布号
CA2714087(A1)
申请公布日期
2009.08.20
申请号
CA20092714087
申请日期
2009.01.22
申请人
MERCK SHARP & DOHME CORP.
发明人
CONVERSO, ANTONELLA;GARBACCIO, ROBERT M.;HARTINGH, TIMOTHY J.;KREATSOULAS, CONSTANTINE;RICKERT, KEITH W.;TASBER, EDWARD S.
