发明名称 NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID
摘要 [PROBLEMS] To provide a compound useful as an amyloid-targeting imaging-diagnostic probe, and also provide a diagnostic agent for Alzheimer's disease comprising the compound. [MEANS FOR SOLVING PROBLEMS] A compound represented by the formula (1) or a salt thereof; and a diagnostic agent for Alzheimer's disease, comprising a compound represented by the formula or a salt thereof. (1) wherein A1, A2, A3 and A4 independently represent a carbon or a nitrogen; R1 represents a radioactive halogen substituent; R2 represents a group selected from the group consisting of a hydrogen, a hydroxyl group, a methoxy group, a carboxyl group, an amino group, an N-methylamino group, an N,N-dimethylamino group and a cyano group; and p represents an integer of 0 to 2, provided that at least one of A1, A2, A3 and A4 represents a carbon and R1 binds to the carbon represented by the at least one of A1, A2, A3 and A4. ® KIPO & WIPO 2009
申请公布号 KR20090083414(A) 申请公布日期 2009.08.03
申请号 KR20097010905 申请日期 2007.08.16
申请人 NIHON MEDI-PHYSICS CO., LTD. 发明人 TANIFUJI SHIGEYUKI;NAKAMURA DAISAKU;TAKASAKI SHINYA;OKUMURA YUKI
分类号 C07D471/04;A61K49/04 主分类号 C07D471/04
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