发明名称 |
Methods and compositions useful for diagnosis, staging, and treatment of cancers and tumors |
摘要 |
<p>Methods, compositions and kits which employ one or more ZEB specific detection reagents for detection and localization of ZEB associated molecules in tumor cells are disclosed. Also provided are methods for determining stage and progression of cancer in a mammal based on alterations in ZEB expression levels and subcellular localization. Also provided are methods for treating a cancer in a mammal by modulating ZEB expression levels and activity.</p> |
申请公布号 |
AU2002339865(A8) |
申请公布日期 |
2009.07.30 |
申请号 |
AU20020339865 |
申请日期 |
2002.08.30 |
申请人 |
THE CHILDREN'S HOSPITAL OF PHILADELPHIA |
发明人 |
THOMAS GENETTA |
分类号 |
C12Q1/66;A01N47/40;A61K48/00;C07H21/00;C07H21/02;C07H21/04;C12N15/63;C12N15/88;C12P19/34;C12Q1/68;G01N33/574 |
主分类号 |
C12Q1/66 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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