| 发明名称 |
PGD2 receptor antagonists for the treatment of inflammatory diseases |
| 摘要 |
Disclosed herein are compounds represented by Structural Formula (I) and (I-A): Also disclosed is the use of such compounds for inhibiting the G-protein coupled receptor referred to as chemoattractant receptor-homologous molecule expressed on Th2, or simply "CRTH2" for the treatment of inflammatory disorders. The variables in Structural Formula (I) and (I-A) are defined herein.
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| 申请公布号 |
US2009181966(A1) |
申请公布日期 |
2009.07.16 |
| 申请号 |
US20090321910 |
申请日期 |
2009.01.27 |
| 申请人 |
|
发明人 |
GHOSH SHOMIR;ELDER AMY M.;CARSON KENNETH G.;SPROTT KEVIN T.;HARRISON SEAN J.;HICKS FREDERICK A.;RENOU CHRISTELLE C.;REYNOLDS DOMINIC |
| 分类号 |
A61K31/47;A61K31/4353;A61K31/5377;A61P37/08;C07D215/42;C07D215/44;C07D401/06;C07D401/10;C07D401/12;C07D405/06;C07D409/06;C07D413/06;C07D413/10;C07D417/06;C07D471/04;C07D491/04;C07D495/04 |
主分类号 |
A61K31/47 |
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