摘要 |
<p>The present invention relates to hydroxy-bisphosphonic acid derivatives corresponding to general formula (I): in which: - n and m denote, independently of one another, an integer ranging from 1 to 4, - X denotes an oxygen atom or an N-R3 group, - R1 and R3 denote, independently of one another, a linear or branched C1 to C6 alkyl group, and - R2 denotes a residue of a molecule of therapeutic or diagnostic interest, or pharmaceutically acceptable salts of said derivatives, and also the method for the preparation thereof and the therapeutic or diagnostic use thereof.</p> |
申请人 |
UNIVERSITE DE NANTES;CHU NANTES;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);EGOROV, MAXIM;FORTUN, YANNICK;HEYMANN, DOMINIQUE;LEBRETON, JACQUES;MATHE, MONIQUE;PADRINES, MARC;REDINI, FRANCOISE |
发明人 |
EGOROV, MAXIM;FORTUN, YANNICK;HEYMANN, DOMINIQUE;LEBRETON, JACQUES;MATHE, MONIQUE;PADRINES, MARC;REDINI, FRANCOISE |