发明名称 |
NOVEL ANTIBODY MOLECULES AND NUCLEIC ACIDS BINDING TO FUNGAL STRESS PROTEIN HSP90 |
摘要 |
<p>An scFv peptide comprising a VH domain and a VL domain linked by an amino acid spacer is disclosed. The VH domain comprises a sequence with at least 80% sequence identity to the sequence of SEQ ID NO. 64. The VL domain comprises a sequence with at least 80% sequence identity to the sequence of SEQ ID NO. 66. The scFv peptide also comprises the substitution or deletion of an amino acid in the VH domain at the position corresponding to C28.</p> |
申请公布号 |
WO2008132134(A9) |
申请公布日期 |
2009.07.09 |
申请号 |
WO2008EP55006 |
申请日期 |
2008.04.24 |
申请人 |
NOVARTIS AG;BURNIE, JAMES;WECHNER, PHILIPP |
发明人 |
BURNIE, JAMES;WECHNER, PHILIPP |
分类号 |
C07K16/14;A61K35/00;A61K39/395;A61P31/00;A61P37/06;C07K16/18;C12N15/10 |
主分类号 |
C07K16/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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