SOLUTION PREPARATION CONTAINING ANTIBODY AT HIGH CONCENTRATION
摘要
A stable solution preparation containing an antibody, which is characterized by containing arginine and methionine, is provided as a stable antibody-containing preparation suitable for subcutaneous administration wherein dimer formation and deamidation are prevented during prolonged storage.
申请公布号
WO2009084659(A1)
申请公布日期
2009.07.09
申请号
WO2008JP73798
申请日期
2008.12.26
申请人
CHUGAI SEIYAKU KABUSHIKI KAISHA;F. HOFFMANN-LA ROCHE AG;MORICHIKA, TOSHIYUKI;KAMEOKA, DAISUKE;IMAEDA, YOSHIMI;MAEDA, TERUTOSHI;STAUCH, OLIVER BORIS
发明人
MORICHIKA, TOSHIYUKI;KAMEOKA, DAISUKE;IMAEDA, YOSHIMI;MAEDA, TERUTOSHI;STAUCH, OLIVER BORIS
