A PREPARATION METHOD OF BIOSENSOR OR GAS-SENSOR USING LIPOSOME

摘要

A method for manufacturing a biosensor or gas sensor using a liposome is provided to combining lipid monolayer containing a functional group for the fixation of receptor and have high fixation efficiency and reproductivity. A method for manufacturing a bio sensor in which a receptor is fixed comprises: a step of adding hydrocarbon compound containing thiol group on the surface of sensor chip and coating self-assembled monolayer; a step of preparing a liposome comprising a functional group for fixation of receptor and lipid; and a step of reacting the liposome on the coated sensor chip and re-coating on the self-assembled monolayer. A material for fixing the receptor comprises a lipid and hydrocarbon containing the functional group for fixation of receptor. The step of preparing the liposome is performed by mixing MBP-PE[1,2-Dipalmitoyl-sn-Glycero-Phosphoethanolamine-N-[4-(p-maleimidophenyl)butyramide] lipid and lipid.