发明名称 |
Multivalent inhibitors of serum amyloid P component |
摘要 |
Novel glycerol cyclic pyruvate derivates were prepared and demonstrated to inhibit the binding of an immobilized D-proline derivative to serum amyloid P component (SAP) have been prepared. As such, the compounds of the invention are useful for treating amyloidosis and diseases associated with amyloidosis, for example Alzheimer&supl;s disease and maturity onset diabetes mellitus.
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申请公布号 |
US7553819(B2) |
申请公布日期 |
2009.06.30 |
申请号 |
US20040556333 |
申请日期 |
2004.05.12 |
申请人 |
THERACARB INC. |
发明人 |
BUNDLE DAVID;KITOV PAVEL;NG KENNETH KAI-SING;HO JASON GAY SHUEN |
分类号 |
A01N43/04;A61K31/70;C07D295/185;C07D303/30;C07D319/06;C07D407/12;C07D407/14;C08B37/00 |
主分类号 |
A01N43/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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