发明名称 Cell permeable peptides for inhibition of inflammatory reactions and methods of use
摘要 The present invention relates to the delivery of biologically active molecules, such as peptides, into the interior of cells by administering to the cells a complex comprising the molecule linked to an importation competent signal peptide. Such delivery can be utilized, for example, to treat and/or prevent inflammatory conditions, e.g., but not limited to, systemic inflammatory reactions such as endotoxic shock, localized inflammatory reactions such as inflammatory skin diseases and conditions, and inflammatory diseases such as autoimmune diseases.
申请公布号 US7553929(B2) 申请公布日期 2009.06.30
申请号 US20030148457 申请日期 2003.02.20
申请人 VANDERBILT UNIVERSITY 发明人 HAWIGER JACK J.;ROBINSON DANIEL;VEACH RUTH ANN;LIU XUE YAN;LIU DANYA;DOWNS SHEILA;COLLINS ROBERT D.;LIN YAO-ZHONG
分类号 C07K7/64;A61K38/00;A61K38/12;A61K38/17;A61K39/00;A61K47/48;C07K14/475;C07K14/50;C12N15/62;C12N15/87 主分类号 C07K7/64
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