Yeast strains with improved fructose fermentation capacity

摘要

Provided is an isolated HXT3 hexose transporter having an improved capacity to transport fructose with respect to the capacity to transport fructose of a specified sequence of wild type hexose transporter and wherein said isolated HXT3 hexose transporter has an amino acid sequence having at least a mutation at position lIe209. Further provided is a similar transporter additionally comprising at least a mutation at a position selected from the group consisting of Met 324, Leu 388, Tyr 389, lie 392, Glu 414, Gly 415, lie 449, Leu 471. Also provided are yeast cells containing the transporter and use of the yeast for fermentation of carbohydrates.