AGENTS WHICH REGULATE, INHIBIT, OR MODULATE THE ACTIVITY AND/OR EXPRESSION OF LYSYL OXIDASE (LOX) AND LOX-LIKE PROTEASES AS A UNIQUE MEANS TO BOTH LOWER INTRAOCULAR PRESSURE AND TREAT GLAUCOMATOUS RETINOPATHIES/OPTIC NEUROPATHIES
摘要
The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least one non-nucleotide or non-protein agent that inhibits expression and/or signaling of lysyl oxidase (LOX) or a lysyl oxidase-like protease (LOXL).
申请公布号
WO2006068829(A9)
申请公布日期
2009.06.25
申请号
WO2005US44220
申请日期
2005.12.05
申请人
ALCON, INC.;SHEPARD, ALLAN;CLARK, ABBOT F.;HELLBERG, MARK