发明名称 |
THE PRESENT INVENTION RELATES TO METHODS FOR PREDICTION OF THE THERAPEUTIC SUCCESS OF BREAST CANCER THERAPY |
摘要 |
<p>The present invention relates to a method for predicting a clinical response of a patient suffering from or at risk of developing gynecologic cancer towards a given mode of treatment, said method comprising the steps of : a) obtaining a biological sample from said patient; b) determining the expression level of at least one gene selected from the group comprising ALCAM, Osteopontin, Her-2/neu, EGFR, uPA/PAI-1 and/or ESRl, in particular of ALCAM and/or Osteopontin, in said sample; c) comparing the pattern of expression level (s) determined in (b) with one or several reference pattern (s) of ex pression levels; and d) predicting therapeutic success for said given mode of treatment in said patient or implementing therapeutic regimen in said patient from the outcome of the comparison in step (c).</p> |
申请公布号 |
WO2009068445(A1) |
申请公布日期 |
2009.06.04 |
申请号 |
WO2008EP65517 |
申请日期 |
2008.11.14 |
申请人 |
SIEMENS HEALTHCARE DIAGNOSTICS GMBH;WIRTZ, RALPH MARKUS;MILDE-LANGOSCH, KARIN;IHNEN, MAIKE;SCHROEDER, CHRISTINE |
发明人 |
WIRTZ, RALPH MARKUS;MILDE-LANGOSCH, KARIN;IHNEN, MAIKE;SCHROEDER, CHRISTINE |
分类号 |
C07K16/00;C12Q1/68;G01N33/574 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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