发明名称 THE PRESENT INVENTION RELATES TO METHODS FOR PREDICTION OF THE THERAPEUTIC SUCCESS OF BREAST CANCER THERAPY
摘要 <p>The present invention relates to a method for predicting a clinical response of a patient suffering from or at risk of developing gynecologic cancer towards a given mode of treatment, said method comprising the steps of : a) obtaining a biological sample from said patient; b) determining the expression level of at least one gene selected from the group comprising ALCAM, Osteopontin, Her-2/neu, EGFR, uPA/PAI-1 and/or ESRl, in particular of ALCAM and/or Osteopontin, in said sample; c) comparing the pattern of expression level (s) determined in (b) with one or several reference pattern (s) of ex pression levels; and d) predicting therapeutic success for said given mode of treatment in said patient or implementing therapeutic regimen in said patient from the outcome of the comparison in step (c).</p>
申请公布号 WO2009068445(A1) 申请公布日期 2009.06.04
申请号 WO2008EP65517 申请日期 2008.11.14
申请人 SIEMENS HEALTHCARE DIAGNOSTICS GMBH;WIRTZ, RALPH MARKUS;MILDE-LANGOSCH, KARIN;IHNEN, MAIKE;SCHROEDER, CHRISTINE 发明人 WIRTZ, RALPH MARKUS;MILDE-LANGOSCH, KARIN;IHNEN, MAIKE;SCHROEDER, CHRISTINE
分类号 C07K16/00;C12Q1/68;G01N33/574 主分类号 C07K16/00
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