发明名称 |
SMART HYDROGEL PARTICLES: BIOMARKER HARVESTING: ONE-STEP AFFINITY PURIFICATION, SIZE EXCLUSION, AND PROTECTION AGAINST DEGRADATION |
摘要 |
A method for biomarker harvesting were an affinity bait molecule is introduced into N- isoproplacrylamide to produce a particle that will perform at least three independent functions within minutes. This incudes a molecular size sieving, affinity capture of all solution phase target molecules, and complete protection of harvested proteins from enzymatic degradation, the captured analytes can then be readily electroeluted for analysis. |
申请公布号 |
WO2009064389(A2) |
申请公布日期 |
2009.05.22 |
申请号 |
WO2008US12666 |
申请日期 |
2008.11.10 |
申请人 |
LUCHINI, ALESSANDRA |
发明人 |
LUCHINI, ALESSANDRA;GEHO, DAVID, H.;PETRICOIN III, EMANUEL;LIOTTA, LANCE, A. |
分类号 |
B01J19/00;G01N33/543;C08J9/16;C12M1/00;G01N21/00;G01N21/64;G01N27/00 |
主分类号 |
B01J19/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|