| 发明名称 |
NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS |
| 摘要 |
The present invention relates to novel compounds of formula (I) wherein W, n, X and W' are defined in the description; invention compounds are modulators of metabotropic glutamate receptors-subtype 5 ("mGluR5") which are useful for the treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors.
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| 申请公布号 |
US2009124625(A1) |
申请公布日期 |
2009.05.14 |
| 申请号 |
US20050630013 |
申请日期 |
2005.06.17 |
| 申请人 |
ADDEX PHARMACEUTICALS SA |
发明人 |
BESSIS ANNE-SOPHIE;BOLEA CHRISTELLE;BONNET BEATRICE;EPPING-JORDAN MARK;POIRIER NICOLAS;POLI SONIA-MARIA;ROCHER JEAN-PHILIPPE;THOLLON YVES |
| 分类号 |
A61K31/498;A61K31/4035;A61K31/4196;A61K31/422;A61K31/423;A61K31/4245;A61K31/426;A61K31/427;A61K31/428;A61K31/437;A61K31/44;A61K31/4427;A61K31/4439;A61K31/47;A61K31/4709;A61K31/502;A61K31/505;A61K31/506;A61P1/00;A61P3/04;A61P25/00;A61P25/28;A61P29/00;C07D213/56;C07D215/00;C07D215/06;C07D233/54;C07D237/30;C07D239/24;C07D239/26;C07D241/36;C07D263/56;C07D277/20;C07D277/22;C07D401/02;C07D401/06;C07D403/06;C07D413/02;C07D413/06;C07D417/06;C07D471/02;C07D471/04;C07D498/02;C07D498/04 |
主分类号 |
A61K31/498 |
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