发明名称 MICE LACKING ALPHA 1G SHOWING ENHANCED NOVELTY-SEEKING AND ALCOHOL PREFERENCE AND THERAPEUTIC METHODS FOR MOOD DISORDERS BY MODULATING ALPHA 1G T-TYPE CALCIUM CHANNELS
摘要 The present invention relates to a novel use of an alpha1G T-type calcium channel transgenic mouse as a nervous disease model, more particularly, a novel use of a mouse deficient in alpha1G T-type calcium channel showing novelty-seeking and alcohol preference as a nervous disease model for human nervous related diseases such as novelty-seeking character, alcoholism, anxiety and emotion disorder by stress, etc. The alpha1G T-type channel transgenic mice showing novelty-seeking and alcohol preference of the present invention can be effectively used for the development of a medicine and a therapeutic method for human nervous diseases.
申请公布号 US2009126031(A1) 申请公布日期 2009.05.14
申请号 US20090351316 申请日期 2009.01.09
申请人 THE KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY 发明人 SHIN HEE-SUP;KIM DAESOO;LEE JUNGRYUN;CHOI SOONWOOK;KIM CHANKI;LEE SUKCHAN
分类号 A01K67/027 主分类号 A01K67/027
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