| 发明名称 |
METHODS FOR EVALUATING GENETIC SUSCEPTIBILITY AND THERAPY FOR CHRONIC INFLAMMATORY DISEASES |
| 摘要 |
The invention discloses a knockout mouse that is homozygous for a RUNX3 null allele, as a novel model for chronic inflammatory disease. The present invention provides methods of diagnosing and assessing predisposition to chronic inflammatory diseases. The present invention further provides methods for testing agents for effectiveness in treating and/or preventing diseases associated with chronic inflammatory or autoimmune conditions.
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| 申请公布号 |
US2009117046(A1) |
申请公布日期 |
2009.05.07 |
| 申请号 |
US20090352460 |
申请日期 |
2009.01.12 |
| 申请人 |
YEDA RESEARCH AND DEVELOPMENT, LTD. |
发明人 |
GRONER YORAM;BETTOUN DAVID |
| 分类号 |
A61K49/00;A01K67/00;A61B;A61B1/00;A61K31/7088;A61K48/00;A61P29/00;A61P43/00;C07H21/04;C12N15/11;C12Q1/00;C12Q1/68;G01N33/00;G01N33/543 |
主分类号 |
A61K49/00 |
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