发明名称 |
(1,4-DIAZA-BICYCLO[3.2.2]NON-6-EN-4-YL)-HETEROCYCLYL-METHANONE LIGANDS FOR NICOTINIC ACETYLCHOLINE RECEPTORS, USEFUL FOR THE TREATMENT OF DISEASE |
摘要 |
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds, which act as ligands for the a7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof. The novel compounds include compounds of formula I: (I) wherein X, R1, and R2 are as herein defined.
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申请公布号 |
CA2703163(A1) |
申请公布日期 |
2009.04.30 |
申请号 |
CA20082703163 |
申请日期 |
2008.10.22 |
申请人 |
MEMORY PHARMACEUTICALS CORPORATION |
发明人 |
HERBERT, BRIAN;SCHUMACHER, RICHARD;DAI, GUANGXIU;XIE, WENGE |
分类号 |
C07D453/00;A61K31/40;A61K31/4045;A61K31/43;A61K31/439;C07D307/78 |
主分类号 |
C07D453/00 |
代理机构 |
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主权项 |
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地址 |
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