发明名称 |
[1,2,4]OXADIAZOLES (VERSIONS), METHODS OF OBTAINING THEM, PHARMACEUTICAL COMPOSITION AND METOD OF INHIBITING ACTIVATION OF METABOTROPIC GLUTAMATE RECEPTORS - 5 |
摘要 |
FIELD: chemistry. ^ SUBSTANCE: described is novel compound of formula (I) ^ or its pharmaceutically acceptable salt, values of radicals are given in invention formula Compound has ability to inhibit receptor mGluR5, which intends it for prevention and/or treatment of receptor mGluR5- associated disturbances. Also described is pharmaceutical composition, method of inhibiting activation of receptors mGluR5, using compound of formula (I). Described is method of obtaining compound of formula 1a or 1b structure. ^ EFFECT: increasing output of suitable product. ^ 18 cl, 825 ex |
申请公布号 |
RU2352568(C2) |
申请公布日期 |
2009.04.20 |
申请号 |
RU20050106844 |
申请日期 |
2003.08.08 |
申请人 |
ASTRAZENEKA AB |
发明人 |
ARORA DZHALAJ;VAL'DMAN MAGNUS;VENSBO DAVID;INGVE UL'RIKA;ISAAK METVIN;JOKHANSSON MARTIN;JJUBAKK KHELENA;KERS ANIKA;MAKLED DONAL'D EH.;MALBERG JOKHAN;MINIDIS ALEKSANDER;OSKARSSON KARIN;OSTERVALL' KRISTOFFER;SIN' TAO;SLASSI ABDEL'MALIK;STEFANATS TOMISLAV;STORMEHN TOMAS M.;EHDVARDS LUIZA |
分类号 |
C07D413/12;A61K31/42;A61K31/421;A61K31/4245;A61P25/00;C07D271/00;C07D413/14;C07D417/14;C07D471/04 |
主分类号 |
C07D413/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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