Extended release coated microtablets of venlafaxine hydrochloride

摘要

An extended release formulation of venlafaxine hydrochloride in the form of minitablets filled in hard gelatin capsule is disclosed, wherein said mini-tablets having a core and an outer coating comprising 2 to 15% of the total weight of the mini-tablets, the core of the said mini-tablets comprising venlafaxine hydrochloride, microcrystalline cellulose and polyvinylpyroolidone, and the said coating comprising a water insoluble polymer and a water soluble polymer.