发明名称 Substituted 2-thio-3,5-dicyano-4-aryl-6-aminopyridines and their use
摘要 The invention relates to compounds of general formula (I), a method for the production thereof and the use thereof as pharmacologically effective substances for a broad medical indication spectrum. Furthermore, selective adenosine receptor ligands, preferably selective adenosine A1-, adenosine A2a- and/or adenosine A2b-receptor ligands are provided for the prophylaxis and/or the treatment of diseases, especially cardiovascular diseases, diseases of the urogenital region, diseases of the respiratory tract, inflammatory and neuroinflammatory diseases, diabetes, especially pancreatic diabetes, neurodegenerative diseases, pain states, cancer as well as liver fibrosis and liver cirrhosis.
申请公布号 US7504421(B2) 申请公布日期 2009.03.17
申请号 US20060359927 申请日期 2006.02.21
申请人 ROSENTRETER ULRICH;HENNING ROLF;BAUSER MARCUS;KRAEMER THOMAS;VAUPEL ANDREA;HUEBSCH WALTER;DEMBOWSKY KLAUS;SALCHER-SCHRAUFSTATTER OLGA;STASCH JOHANNES-PETER;KRAHN THOMAS;PERZBORN ELISABETH 发明人 ROSENTRETER ULRICH;HENNING ROLF;BAUSER MARCUS;KRAEMER THOMAS;VAUPEL ANDREA;HUEBSCH WALTER;DEMBOWSKY KLAUS;SALCHER-SCHRAUFSTATTER OLGA;STASCH JOHANNES-PETER;KRAHN THOMAS;PERZBORN ELISABETH
分类号 C07D213/85;A61K31/44;A61K31/4418;A61K31/443;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4545;A61K31/4709;A61K31/496;A61K31/5377;A61P1/16;A61P3/10;A61P9/10;A61P11/00;A61P13/00;A61P15/00;A61P25/00;A61P25/04;A61P29/00;A61P35/00;A61P43/00;C07D401/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12 主分类号 C07D213/85
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