| 摘要 |
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture. |
| 申请人 |
ABBOTT LABORATORIES;PLA, ITZCOATL, A.;MATUCK, JOSEPH, C.;FANN, JOHN, C.;SCHULZ, CHRISTOF;ROY, NICOLE, A.;BRUTON, DAVID F.;MCINTIRE, JAMES;CHANG, YU-HSIANG, DAVID;SEEWOESTER, THOMAS |
发明人 |
PLA, ITZCOATL, A.;MATUCK, JOSEPH, C.;FANN, JOHN, C.;SCHULZ, CHRISTOF;ROY, NICOLE, A.;BRUTON, DAVID F.;MCINTIRE, JAMES;CHANG, YU-HSIANG, DAVID;SEEWOESTER, THOMAS |
