发明名称 |
COMPOSITION FOR TREATING SULFUR MUSTARD TOXICITY AND METHODS OF USING SAME |
摘要 |
One embodiment of the present invention provides a composition, comprising, in amounts effective to treat sulfur mustard or half sulfur mustard induced toxicity or skin damage: an agent that inhibits alkylation of -SH and >NH protein groups; an agent that reduces -SS- to SH; a scavenger of reactive oxygen species; a substrate that maintains tissue reduction-oxidation status; an agent that protects against invading inflammatory cells and associated oxidative stress; an antagonist of prostaglandin synthesis; and an agent that induces tissue regeneration. Methods of using the composition are also provided.
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申请公布号 |
US2009048153(A1) |
申请公布日期 |
2009.02.19 |
申请号 |
US20050720283 |
申请日期 |
2005.12.02 |
申请人 |
UNIVERSITY OF MARYLAND, BALTIMORE;THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY |
发明人 |
VARMA SHAMBHU D.;PETRALI JOHN |
分类号 |
A61K38/28;A01N37/12;A61K31/185;A61K31/355;A61K31/405;A61K31/56;A61K31/7004 |
主分类号 |
A61K38/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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