发明名称 INDOLE AND DIHYDROINDOLE DERIVATIVES
摘要 The present invention relates to compounds of formula (I) wherein U, A1, A2, A3, A4, A5, A6, A7, L, V, X, n and the bond ===== between the carbon atom Ca and the carbon atom Cb are as defined in the description and claims, and pharmaceutically acceptable salts and/or pharmaceutically acceptable esters thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hyper cholesterolemia, hyperlipemia, arteriosclerosis, vascular diseases, mycoses, gallstones, tumors and/or hyperproliferative disorders, and treatme nt and/or prophylaxis of impaired glucose tolerance and diabetes.
申请公布号 CA2428315(C) 申请公布日期 2009.02.17
申请号 CA20012428315 申请日期 2001.11.21
申请人 F. HOFFMANN-LA ROCHE AG 发明人 ACKERMANN, JEAN;AEBI, JOHANNES;WELLER, THOMAS;PANDAY, NARENDRA;DEHMLOW, HENRIETTA;MORAND, OLIVIER
分类号 C07D209/08;A61K31/404;A61K31/422;A61K31/425;A61K31/427;A61K31/4439;A61K31/454;A61K31/506;A61K31/5377;A61P1/16;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P31/10;A61P33/00;A61P35/00;A61P43/00;C07D401/12;C07D403/12;C07D413/12;C07D417/12 主分类号 C07D209/08
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