| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a new and improved method for producing isolated homozygous stem cells usable as cells for cell therapy and therapeutic transplantation, chunk of cells, resource of cells for producing a tissue and an organ. <P>SOLUTION: Disclosed are pluripotent homozygous stem (HS) cells, and methods and materials for making the same. Further provided are methods for differentiation of HS cells into progenitor (multipotent) cells or other desired cells, groups of cells or tissues. Further, the applications of the HS cells disclosed herein, include (but are not limited to) the diagnosis and treatment of various diseases (for example, genetic diseases, neurodegenerative diseases, endocrine-related disorders and cancer), traumatic injuries, cosmetic or therapeutic transplantation, gene therapy and cell replacement therapy. <P>COPYRIGHT: (C)2009,JPO&INPIT |
