发明名称 |
CYTOTOXIC AGENTS COMPRISING NEW TOMAYMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE |
摘要 |
The invention relates to novel tomaymicine derivatives comprising a linker. It also relates to the conjugate molecules that comprise one or more of said tomaymicine derivatives covalently linked to a cell binding agent through a linking group that is present on the linker of the tomaymycin derivative. It also relates to the preparation of the tomaymicine derivatives and of the conjugate molecules.
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申请公布号 |
CA2693551(A1) |
申请公布日期 |
2009.02.05 |
申请号 |
CA20082693551 |
申请日期 |
2008.07.18 |
申请人 |
SANOFI-AVENTIS |
发明人 |
BOUCHARD, HERVE;CHARI, RAVI V.J.;COMMERCON, ALAIN;DENG, YONGHONG;GAUZY, LAURENCE |
分类号 |
C07D487/04;A61K31/5517;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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