COMBINATIONS FOR THE TREATMENT OF B-CELL PROLIFERATIVE DISORDERS

摘要

The invention features compositions and methods employing combinations of an A2A receptor agonist and a PDE inhibitor for the treatment of a B-cell proliferative disorder, e g, multiple myeloma In at least one embodiment, the compositions of the invention comprise a PDE inhibitor active against at least two of PDE 2, 3,4, and 7 In at least one embodiment, the compositions of the invention compnse further administenng an antiproliferative compound.