发明名称 |
Nucleoside based proliferation imaging markers |
摘要 |
Disclosed herein are novel radiolabeled nucleosides and methods for detecting cellular proliferation in a mammal, the method comprising administrating an effective amount of a radiolabeled nucleoside; the method comprising: a) administering to the mammal a diagnostically effective amount of the nucleoside to the mammal; b) allowing the nucleoside to distribute into the effective tissue; and c) imaging the tissue, wherein an increase in binding of the compound to tissue compared to a normal control level of binding indicates that the mammal is suffering from a disease involving cellular proliferation.
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申请公布号 |
US2009016958(A1) |
申请公布日期 |
2009.01.15 |
申请号 |
US20080074538 |
申请日期 |
2008.03.03 |
申请人 |
KOLB HARTMUTH C;WALSH JOSEPH C;YEH ROBERT M;CHEN KAI;GANGADHARMATH UMESH;DUCLOS BRIAN;MOCHARLA VANI P;KARIMI FARHAD;PADGETT HENRY C;LIANG QIANWA;ZHAO TIEMING |
发明人 |
KOLB HARTMUTH C.;WALSH JOSEPH C.;YEH ROBERT M.;CHEN KAI;GANGADHARMATH UMESH;DUCLOS BRIAN;MOCHARLA VANI P.;KARIMI FARHAD;PADGETT HENRY C.;LIANG QIANWA;ZHAO TIEMING |
分类号 |
A61K51/04;C07H19/06;G01N33/53 |
主分类号 |
A61K51/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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