发明名称 |
Acidic insulin preparations having improved stability |
摘要 |
The invention relates to a pharmaceutical formulation comprising a polypeptide selected from the group consisting of insulin, an insulin metabolite, an insulin analog, an insulin derivative and combinations thereof; a surfactant or combinations of two or more surfactants; optionally a preservative or combinations of two or more preservatives; and optionally an isotonicizing agent, buffers or further excipients or combinations thereof, the pharmaceutical formulation having a pH in the acidic range.
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申请公布号 |
US7476652(B2) |
申请公布日期 |
2009.01.13 |
申请号 |
US20050089777 |
申请日期 |
2005.03.25 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
BRUNNER-SCHWARZ ANETTE;LILL NORBERT |
分类号 |
A61K9/08;A61K38/28;A61K9/00;A61K45/08;A61K47/02;A61K47/04;A61K47/08;A61K47/10;A61K47/12;A61K47/14;A61K47/26;A61K47/34;A61K47/36;A61K47/42;A61P3/10 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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