发明名称 A HYBRID DRUG DELIVERY CARRIER LABELED WITH CANCER CELL SPECIFIC LIGAND, A PROCESS FOR THE PREPARATION THEREOF, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
摘要 A hybrid drug delivery carrier is provided to improve the selectivity about the cancer cell and to maximize the effect of medicine while remarkably reducing the cytotoxin about the normal cell. A hybrid drug delivery carrier is strongly adhered with a cancer cell specific ligand to the surface of the metal double layer hydroxide through a covalent bond. The divalent metal of the metal double layer hydroxide is selected from the group consisting of magnesium (Mg^2+), calcium (Ca^2+), zinc (Zn^2+) and their combination. The trivalent metal comprising a metal double layer hydroxide is selected from a group consisting of aluminium (Al^3+), iron (Fe^3+) and their combination.
申请公布号 KR20080113473(A) 申请公布日期 2008.12.31
申请号 KR20070061994 申请日期 2007.06.25
申请人 EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION 发明人 CHOY, JIN HO;LEE, GO EUN;KIM, JUNG EUN;CHOI, SOO JIN;OH, JAE MIN
分类号 A61K33/30;A61K33/06;A61P35/00 主分类号 A61K33/30
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