发明名称 |
A HYBRID DRUG DELIVERY CARRIER LABELED WITH CANCER CELL SPECIFIC LIGAND, A PROCESS FOR THE PREPARATION THEREOF, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME |
摘要 |
A hybrid drug delivery carrier is provided to improve the selectivity about the cancer cell and to maximize the effect of medicine while remarkably reducing the cytotoxin about the normal cell. A hybrid drug delivery carrier is strongly adhered with a cancer cell specific ligand to the surface of the metal double layer hydroxide through a covalent bond. The divalent metal of the metal double layer hydroxide is selected from the group consisting of magnesium (Mg^2+), calcium (Ca^2+), zinc (Zn^2+) and their combination. The trivalent metal comprising a metal double layer hydroxide is selected from a group consisting of aluminium (Al^3+), iron (Fe^3+) and their combination.
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申请公布号 |
KR20080113473(A) |
申请公布日期 |
2008.12.31 |
申请号 |
KR20070061994 |
申请日期 |
2007.06.25 |
申请人 |
EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION |
发明人 |
CHOY, JIN HO;LEE, GO EUN;KIM, JUNG EUN;CHOI, SOO JIN;OH, JAE MIN |
分类号 |
A61K33/30;A61K33/06;A61P35/00 |
主分类号 |
A61K33/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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