发明名称 IN VITRO EXAMINATION METHOD FOR EARLY PHARMACOCYTOKINETICS OF PHARMACEUTICAL PREPARATIONS
摘要 FIELD: medicine; pharmacology. ^ SUBSTANCE: invention relates to examination and analysis of interaction between pharmaceutical preparations and living cell cultures, using scanning optical confocal microscopy, particularly to examination of entry, accumulation and distribution pharmacocytokinetics of fluorescent dye marked pharmaceutical in living cells. Applied result consists in widening field of utilisation, and is achieved by the method proposed, based on vital confocal cells scanning, treated with the pharmaceutical, accompanied with metabolic changes dynamics analysis and living cells structure condition, affected by the pharmaceutical taken in and distributed. ^ EFFECT: widening field of utilisation. ^ 2 ex, 5 dwg
申请公布号 RU2342654(C1) 申请公布日期 2008.12.27
申请号 RU20070113034 申请日期 2007.04.10
申请人 NEKOMMERCHESKAJA ORGANIZATSIJA UCHREZHDENIE "PROGRESSIVNYE MEDITSINSKIE ISSLEDOVANIJA" 发明人 FILINOVA ELENA JUR'EVNA;ANASHKINA EKATERINA NIKOLAEVNA
分类号 G01N33/15;G01N21/64 主分类号 G01N33/15
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