发明名称 |
METHODS FOR DETERMINING HEPATOCELLULAR CARCINOMA SUBTYPE AND DETECTING HEPATIC CANCER STEM CELLS |
摘要 |
The invention provides a method of determining an HCC subtype in a subject comprising a) obtaining a sample from the subject, b) assaying the sample to detect the expression of 1 or more biomarkers, and c) correlating the expression of the biomarkers with an HCC subtype in a subject. The invention further provides methods of detecting HCC stem cells in a sample. Additionally, the invention provides methods and compositions for treating subjects with HCC that take advantage of the biomarkers associated with HCC stem cells. |
申请公布号 |
CA2690144(A1) |
申请公布日期 |
2008.12.18 |
申请号 |
CA20082690144 |
申请日期 |
2008.06.09 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SEC RETARY OF DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION |
发明人 |
WANG, XIN WEI;JI, JUNFANG;YAMASHITA, TARO;CROCE, CARLO M. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|