发明名称 |
PROCESS FOR PREPARING 4-/3-ALKYNYL-OXY-2-HYDROXY-PROPYL/-PIPERAZIN-1-Y1-N-PHENYL-ACETAMIDE DERIVATIVES |
摘要 |
1. Compounds of the formula : see diagramm : EP0143016,P9,F1 wherein R1 represents hydrogen or an alkyl radical linear or branched having 1-6 C atoms ; R2 and R3 represent separately a phenyl radical, an alkyl radical linear or branched having 1-6 C atoms, or together with the carbon atom to which they are bounded a cycloalkyl radical of 5 to 7 C atoms ; R4 represents hydrogen or an alkyl radical linear or branched having 1-6 C atoms ; R5 represents an alkyl radical linear or branched having 1-6 C atoms or phenyl radical optionally substituted by a halogen atom ; X represents hydrogen or halogen atom, and pharmaceutically acceptable addition salts thereof. |
申请公布号 |
HUT35253(A) |
申请公布日期 |
1985.06.28 |
申请号 |
HU19840003473 |
申请日期 |
1984.09.14 |
申请人 |
CERM CENT EUROP RECH MAUVERNAY |
发明人 |
COMBOURIEU,MICHAEL,FR;LAIGLE,JEAN-CLAUDE,FR;REYJAL,JEAN-FRANCOIS,FR;LANDES,MARIE-PAULE,FR |
分类号 |
C07D295/14;A61K31/495;A61P9/08;A61P9/10;C07D295/15 |
主分类号 |
C07D295/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|