| 发明名称 |
18F-LABELLED FOLATES |
| 摘要 |
<p>The present invention is directed towards a new method of synthesis of 18 F-folate radiopharmaceuticals, wherein fluorine-18 is attached to a pteroate (or folate) or derivative thereof, through direct radiolabeling with 18 [F] fluoride, as well as 18F-folate radiopharmaceuticals obtained by such metho d of synthesis and their use in diagnosis and monitoring of cancer therapy a nd therapy of inflammatory and autoimmune diseases.</p> |
| 申请公布号 |
CA2670363(A1) |
申请公布日期 |
2008.10.23 |
| 申请号 |
CA20082670363 |
申请日期 |
2008.04.11 |
| 申请人 |
MERCK EPROVA AG |
发明人 |
AMETAMEY, SIMON MENSAH;MOSER, RUDOLF;ROSS, TOBIAS LUDWIG;GROEHN, VIOLA;PHOEBE, LAM |
| 分类号 |
C07B59/00;A61B5/00;C07D475/04 |
主分类号 |
C07B59/00 |
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