| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a useful peptide capable of intruding into a mammalian cell relating to the infection mechanism of Mycobacterium leprae which is a causing bacterium of Hansen's disease; a nucleic acid encoding the peptide; a material transfer agent and a material transfer method for efficiently introducing a material into a mammalian cell; and a vaccine, antibody and medicine for effectively preventing or treating an infectious disease caused by Mycobacterium leprae. <P>SOLUTION: There are provided a peptide composed of the whole or a part of a specific amino acid sequence and capable of intruding into a mammalian cell, a peptide having an amino acid sequence obtained by the deletion, substitution or addition of one or more amino acids in the whole or a part of the above amino acid sequence, and a nucleic acid encoding the peptide; a material transfer agent and a material transfer method to use the peptide; and a vaccine, antibody and medicine for the prevention or treatment of infectious diseases caused by Mycobacterium leprae by using the peptide. <P>COPYRIGHT: (C)2008,JPO&INPIT |
