<p>The present invention relates to a pharmaceutical composition comprising (a) a polynucleotide comprising or consisting of a nucleotide sequence encoding a polypeptide with the amino acid sequence as set forth in SEQ ID NO: 2; (b) a polynucleotide comprising or consisting of a nucleotide sequence which is a fragment of a nucleotide sequence encoding the polypeptide with the amino acid sequence as set forth in SEQ ID NO: 2, wherein the polypeptide encoded by said polynucleotide has arteriogenic activity; (c) a polynucleotide comprising or consisting of a nucleotide sequence encoding a polypeptide, wherein said polypeptide exhibits at least 70% sequence identity with the sequence of the polypeptide encoded by the polynucleotide of (a) or (b) over the entire length, and wherein said polypeptide has arteriogenic activity; and/or (d) a polypeptide encoded by the polynucleotide of any one of (a) to (c).</p>
申请公布号
EP1998797(A1)
申请公布日期
2008.12.10
申请号
EP20070703570
申请日期
2007.03.01
申请人
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. BERLIN
发明人
SCHAPER, WOLFGANG;EITENMUELLER, INKA;TROIDL, KERSTIN;TROIDL, CHRISTIAN;HEIL, MATTHIAS;SCHMITZ-RIXEN, THOMAS;HORREVOETS, ANTON, J., G.