发明名称 |
Fermentative preparation process for cytostatics and crystal forms thereof |
摘要 |
<p>The invention relates to a process for concentrating epothilones in a culture medium for the biotechnological preparation of these compounds, the process comprising microorganisms which produce these compounds, wherein one or more cyclodextrins are added to the medium as the complex-forming component. The culture medium and process for the production of epothilones are described too.</p> |
申请公布号 |
SK286517(B6) |
申请公布日期 |
2008.12.05 |
申请号 |
SK20000001240 |
申请日期 |
1999.02.17 |
申请人 |
NOVARTIS AG |
发明人 |
HOFMANN HANS;MAHNKE MARION;MEMMERT KLAUS;PETERSEN FRANK;SCHUPP THOMAS;KUSTERS ERNST;MUTZ MICHAEL |
分类号 |
A61K31/427;A61P35/00;A61P35/04;A61P43/00;B01D15/08;C07D493/04;C12N1/14;C12P;C12P17/16;C12P17/18;C12R1/01;C12R1/645 |
主分类号 |
A61K31/427 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|