发明名称 |
ERYTHROPOIETIN DRUG DELIVERY SYSTEM |
摘要 |
Biodegradable polymer microspheres, preferably formed of zein, are used for in vivo release of erythropoietin (EPO). Ex-amples demonstrate administration of the EPO in zein and polylactides and polymer microspheres to dogs and monkeys, with appropriate increases in blood levels and an increase in reticulocyte counts .
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申请公布号 |
CA2136434(C) |
申请公布日期 |
2008.12.02 |
申请号 |
CA19932136434 |
申请日期 |
1993.06.09 |
申请人 |
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发明人 |
BERNSTEIN, HOWARD;MATHIOWITZ, EDITH;MORREL, ERIC;BRICKNER, AVRAM |
分类号 |
A61K9/00;A61K38/22;A61K9/16;A61K9/50;A61K9/51;A61K9/52;A61K38/17;A61K38/18;A61K47/02;A61K47/12;A61K47/18;A61K47/26;A61K47/32;A61K47/34;A61K47/42 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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