摘要 |
The invention relates to the discovery, identification and use of laminin, laminin-derived protein fragments, and laminin-derived polypeptides, as well as related peptides and antibodies, for the therapeuti c intervention and diagnosis of Alzheimer's disease and other amyloidoses. In addition, the discovery and identification of an Alzheimer's beta-amyloid protein specific binding within the globular domain repeats of the laminin A chain, had led to new diagnostic and therapeutic applications for Alzheimer's disease and other amyloidoses which are disclosed.
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