发明名称 |
OXA1P enhanced protein secretion |
摘要 |
<p>The present invention provides methods and compositions for the efficient and enhanced secretion of a protein of interest from a host cell. In specific, proteins are secreted through the Sec-dependent pathway, involving the spoIIIJ and/or yqjG gene product(s). In some embodiments, expression of the spoIIIJ and/or yqjG gene product(s) is modulated by a promoter operably linked to the gene.</p> |
申请公布号 |
EP1992686(A1) |
申请公布日期 |
2008.11.19 |
申请号 |
EP20080012307 |
申请日期 |
2002.12.12 |
申请人 |
GENENCOR INTERNATIONAL, INC. |
发明人 |
BRON, SIERD;TJALSMA, HAROLD;VAN DIJL, JAN M. |
分类号 |
C12N5/02;C07K14/32;C12N1/21;C12N15/31;C12N15/74;C12N15/75;C12P21/02;C12P21/04;C12P21/06 |
主分类号 |
C12N5/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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