发明名称 Substituted pyrimidines as ligands of adenosine receptors
摘要 The invention provides a compound of formula (I) wherein R and R' are selected from hydrogen, alkyl, alkenyl, alkynyl, or aryl; R'' and R''' are selected from hydrogen, acyl, thio-acyl, seleno-acyl, alkyl, alkenyl, alkynyl, or aryl; or a pharmaceutically acceptable salt thereof, to interact with the adenosine receptors in the beneficial treatment and/or prevention of a (dis)order arising from the said receptors. The invention further provides pharmaceutical compositions comprising said compounds. The invention also relates to the use of said compositions for treating an/or preventing a variety of diseases.
申请公布号 US7449470(B2) 申请公布日期 2008.11.11
申请号 US20060574436 申请日期 2006.04.03
申请人 UNIVERSITEIT LEIDEN 发明人 CHANG LISA CHUNG WAI;IJZERMAN ADRIAAN P.;BRUSSEE JOHANNES
分类号 C07D239/42;A61K31/505;A61P9/00;A61P11/00;A61P25/00;A61P35/00 主分类号 C07D239/42
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