摘要 |
A filament comprising a biocompatible material and a bioactive agent, adapted for implantation within the tissue of a patient wherein the bioactive agent is released over a period of time, is provided. An array of a plurality of the filaments implanted within the tissue of a patient, an array assembler, and a matrix comprising a plurality of filaments and a base adapted for implantation within the tissue of a patient, are further provided. A method for treatment of a malcondition in a patient comprises implantation of a filament, an array of filaments, or a matrix. The bioactive agent can be a chemotherapeutic agent or a radiotherapeutic agent. A radiotherapeutic agent is 123I- or 125I-IUDR, for example in treatment of an advanced stage localized brain tumor such as glioblastoma multiforme. |
申请人 |
PEAK BIOSCIENCES, INC.;REGENTS OF THE UNIVERSITY OF COLORADO;WARREN, STEPHEN, L.;GOULD, GREGORY, A.;LILLEHEI, KEVIN, O. |
发明人 |
WARREN, STEPHEN, L.;GOULD, GREGORY, A.;LILLEHEI, KEVIN, O. |