发明名称 Method For Identifying Agents Which Modulate GtpPase Activity Involved in Insulin-Stimulated Glut4 Translocation
摘要 The present invention is a method for identifying agents that modulate the GTPase activity of AS160. In the instant assay, AS160 or the GAP domain thereof is contacted with a test agent, in the presence of GTP-bound Rab (2A, 8A, 8B, 10, or 14), and the AS160 GAP domain-mediated hydrolysis of GTP to GDP is monitored.
申请公布号 US2008268487(A1) 申请公布日期 2008.10.30
申请号 US20060817819 申请日期 2006.03.08
申请人 TRUSTEES OF DARTMOUTH COLLEGE 发明人 LIENHARD GUSTAV E.;KANE SUSAN;MIINEA CHRISTINEL P.;SANO HIROYUKI
分类号 C12Q1/34 主分类号 C12Q1/34
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