发明名称 |
TWO BIOMARKERS FOR DIAGNOSIS AND MONITORING OF ATHEROSCLEROTIC CARDIOVASCULAR DISEASE |
摘要 |
The present invention identifies two circulating proteins that have been newly identified as being differentially expressed in atherosclerosis. Circulating levels of these two proteins, particularly as a panel of proteins, can discriminate patients with acute myocardial infarction from those with stable exertional angina and from those with no history of atherosclerotic cardiovascular disease. Such levels can also predict cardiovascular events, determine the effectiveness of therapy, stage disease, and the like. For example, these markers are useful as surrogate biomarkers of clinical events needed for development of vascular specific pharmaceutical agents.
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申请公布号 |
WO2008080126(A3) |
申请公布日期 |
2008.10.16 |
申请号 |
WO2007US88707 |
申请日期 |
2007.12.21 |
申请人 |
AVIIR, INC.;TABIBIAZAR, RAYMOND;HYTOPOULOS, EVANGELOS |
发明人 |
TABIBIAZAR, RAYMOND;HYTOPOULOS, EVANGELOS |
分类号 |
G01N33/48 |
主分类号 |
G01N33/48 |
代理机构 |
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地址 |
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