VERFAHREN UND KIT ZUM NACHWEIS ODER ZUR BESTIMMUNG VON 3,4-METHYLENDIOXYMETHAMPHETAMIN

摘要

The present invention describes a hapten derivatised with a crosslinker at the N-position of MDMA. The present invention provides an immunogen comprising the aforementioned hapten, coupled to an antigenicity-conferring carrier material, as well as, conjugates comprising the aforementioned hapten covalently bonded to a detectable labelling agent. In addition, the present invention concerns antibodies raised against the aforementioned immunogens. Finally, the present invention relates to methods and kits for detecting or determining MDMA and N-alkylated derivatives of methylenedioxyamphetamine in biological fluids. The antibodies of the present invention do not significantly cross-react with amphetamine and methamphetaminc.