THE USE OF A TYPE II TRANSMEMBRANE PROTEIN DESIGNATED FIBCD1 AS AN ENDOCYTOSIS RECEPTOR OF ACETYLATED COMPOUNDS

摘要

A type II transmembrane protein designated FIBCD1 is used as an endocytosis receptor of acetylated compounds. More specifically the FIBCD1 is used in a method of transporting a compound, especially a drug, over the epithelium of the small intestine. Thereby the uptake of acetylated drug compounds through the wall of the small intestine is improved. Since the small intestine is the site where the majority of drug substances are taken up by the body, the method of the invention is useful in the future administration of pharmaceuticals to humans.