| 摘要 |
A continuous intravenous analyte monitoring system includes an amperometric biosensor detecting an analyte concentration in the blood, a controller receiving a signal from the biosensor and computing the concentration, and an isolation device isolating the biosensor from EMI. A CPU may be coupled to the controller via the isolation device for continuous output of sensed concentration to a display unit. Isolated circuits may include a temperature sensor transmitting biosensor temperature to the controller for correction of the computed concentration, a multiplexer combining biosensor and temperature sensor signals, and an A/D converter converting multiplexed input to the controller. The biosensor may be a multi-electrode sensor having a working electrode immobilizing an glucose oxidase enzyme to detect blood glucose concentration. The biosensor and temperature sensor may be located in vivo using a catheter for continuous monitoring.
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