COMPRESSIBLE RESILIENT GRANULES AND FORMULATIONS PREPARED THEREFROM

摘要

The present invention provides resilient self-adhering granules which comprise a polysaccharide present in an amount from about 10 wt% to about 90wt% and a binder having a viscosity from about 5,000mPa.s to about 25O1OOOmPa. s present in an amount from about 90wt% to about 10wt%, wherein the granule is capable of reversible agglomeration at or below 6,500 kilonewtons/m2. The present invention also provides oral dosage compositions comprising the resilient self-adhering granules and methods for making and using the resilient self-adhering granules.