发明名称 TOPICAL CORNEAL ANALGESIA USING NEUROTENSIN RECEPTOR AGONISTS AND SYNERGISTIC NEUROTENSIN COMBINATIONS WITHOUT DELAYING WOUND HEALING
摘要 A method for administering an ocular analgesic is described. The method i ncludes the steps of providing a topical analgesic that includes a neo-trypt ophan-containing neurotensin analog and applying the topical analgesic to th e ocular tissue in a dose of about 0.0005 to about 1.2 mg, alternatively abo ut 0.0005 to about 1.0 mg, alternatively about 0.00075 to about 1.0 mg, alte rnatively about 0.001 mg to about 1.0 mg, alternatively about 0.001 mg to ab out 0.8 mg, alternatively about 0.001 mg to about 0.7 mg, alternatively abou t 0.001 mg to about 0.6 mg. Methods of administering a topical analgesic con taining a neo-tryptophan-containing neurotensin analog are also described. T he topical analgesic can be administered in a patch, gel, lotion, spray, or mist.
申请公布号 CA2680704(A1) 申请公布日期 2008.09.18
申请号 CA20082680704 申请日期 2008.03.12
申请人 MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH;SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH;SARENTIS THERAPEUTICS, INC. 发明人 PASTERNAK, GAVRIL W.;RICHELSON, ELLIOTT;BARBUT, DENISE
分类号 A01N37/18;A61K38/00 主分类号 A01N37/18
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